| Product Name | Type III, Type IV, Type XVII Chimeric Collagen |
| Product Specification | 10g/bag |
| Product Appearance | Freeze-dried fibers/Fibrous powder |
| Performance Advantages | Fully exposed active sites Fused core active domains of multiple collagen types |
| Application Scope | Water Emulsion Essence Eye cream Face cream Freeze-dried powder Face mask Spray Scalp care |
Elevate your skincare and personal care formulations with our innovative Triple Chimeric Collagen (Type III/IV/XVII) , presented as a lyophilized fibrous powder engineered for maximum bioactivity. This rationally designed fusion protein combines the functional domains of three essential collagen types into a single molecule, with active sites fully exposed to ensure optimal interaction with skin cells and extracellular matrix components.
Chimeric Design Rationale:
Type III Domain (Elasticity & Healing): Provides the flexible scaffold essential for skin compliance and early wound healing; regulates matrix architecture and mechanosensing to minimize scar formation .
Type IV Domain (Basement Membrane Network): Enables self-assembly into amorphous, felt-like matrices that anchor epidermal cells and maintain dermal-epidermal junction integrity .
Type XVII Domain (Stem Cell Anchoring): Functions as a transmembrane anchor, maintaining hair follicle stem cell quiescence and immaturity while supporting melanocyte stem cell niche function .
Product Advantages for Cosmetic Applications:
Fully Exposed Active Sites: The lyophilized fibrous morphology preserves native conformation, ensuring RGD, GER, and other cell-binding motifs are readily accessible for receptor interaction.
Ultra-Low Endotoxin: ≤0.5 EU/mg, ensuring safety for sensitive skin applications.
Exceptional Purity: >99% via HPLC, free from animal-derived contaminants.
Versatile Formulation Compatibility: The fibrous powder disperses readily in aqueous and emulsion systems, suitable for the full spectrum of personal care products.
Ideal for Formulating:
Serums & Essences: Delivers bioactive collagen directly to the epidermis.
Emulsions & Creams: Enhances skin feel and provides sustained bioactivity.
Lyophilized Powders: Ready-to-use for DIY or professional mixing.
Sheet Masks & Sprays: Ensures even distribution and rapid absorption.
Custom blending and formulation support available for cosmetic manufacturers seeking next-generation active ingredients.