Hexapeptide-11 – ≥98% purity signal peptide. Protects fibroblasts from premature senescence, stimulates collagen & elastin synthesis, enhances skin barrier function & provides antioxidant defense. Clinically proven to reduce wrinkles & improve elasticity. Ideal for anti-aging serums, creams & eye treatments. Request samples!
Product Title
Hexapeptide-11 (FVAPFP) | Yeast-Derived Signal Peptide for Anti-Aging, Firming & Antioxidant Defense
Product Name: Hexapeptide-11
INCI Name: Hexapeptide-11
CAS No.: 161258-30-6
Amino Acid Sequence: H-Phe-Val-Ala-Pro-Phe-Pro-OH (FVAPFP)
Purity: ≥98%
Appearance: White fine powder
Grade: Cosmetic Grade
Recommended Usage: 0.003% – 0.5%
Shelf Life: 24 months
Product Overview
Hexapeptide-11 is a synthetic signal peptide composed of six amino acids — phenylalanine, valine, alanine, proline, and phenylalanine (FVAPFP) . Originally isolated from Saccharomyces cerevisiae (baker‘s yeast) fermentation extracts, it is now produced through high-purity solid-state synthesis for cosmetic applications .
As a signaling peptide, Hexapeptide-11 functions as a bioactive messenger that communicates directly with skin cells to trigger regeneration and repair. Its unique mechanism targets cellular senescence — the biological aging of cells — by reversibly downregulating key proteins (ATM and p53) associated with DNA damage and cellular aging. This makes Hexapeptide-11 a cell-level anti-aging solution that addresses the root causes of skin aging rather than merely treating surface symptoms.
Our Hexapeptide-11 is manufactured to ≥98% purity under strict quality control, offering formulators a high-potency, scientifically validated active ingredient for premium anti-aging skincare products.
Key Specifications
| Parameter |
Specification |
| Product Name |
Hexapeptide-11 |
| INCI Name |
Hexapeptide-11 |
| CAS No. |
161258-30-6 |
| Amino Acid Sequence |
H-Phe-Val-Ala-Pro-Phe-Pro-OH (FVAPFP) |
| Purity |
≥98% |
| Appearance |
White fine powder |
| Grade |
Cosmetic Grade |
| Solubility |
Water-soluble |
| Recommended Usage |
0.003% – 0.5% |
| Storage |
Sealed, protected from light, stored in cool, dry, well-ventilated area (2–8°C recommended)
|
| Packaging |
1g/bag, 1kg/aluminum foil bag, custom available |
| Shelf Life |
24 months |
Key Benefits
| Benefit |
Description |
| Elastin Production |
Stimulates elastin synthesis for skin bounce and resilience |
| Skin Firming |
Rebuilds dermal matrix for enhanced density and firmness |
| Wrinkle Reduction |
Smooths fine lines and deep wrinkles |
| Antioxidant Protection |
Enhances natural antioxidant capacity and protects against UV damage |
| Skin Thickening |
Reinforces the epidermis and strengthens dermal structure |
| Safe & Non-Irritating |
Naturally occurring in the human body; low risk of irritation |
Application Scenarios
| Application |
Typical Formats |
Recommended Usage |
| Anti-Aging Serums & Essences |
Water-based serums, ampoules, concentrates |
0.002% – 0.5% |
| Firming & Lifting Creams |
Day creams, night creams, moisturizers |
0.002% – 0.5% |
| Eye Contour Treatments |
Eye creams, eye serums, eye gels |
0.002% – 0.5% |
| Sheet Masks & Hydrogel Patches |
Face masks, eye patches |
0.002% – 0.5% |
| Barrier Repair Moisturizers |
Advanced moisturizers for barrier strengthening |
0.002% – 0.5% |
| Antioxidant Defense Formulations |
Protective day creams, anti-pollution serums |
0.002% – 0.5% |
| Post-Procedure Recovery Products |
Soothing gels, recovery balms |
0.002% – 0.5% |
Formulation Guidelines:
Solubility: Water-soluble; add to the water phase or during cool-down below 40°C
Optimal pH Range: 4.5 – 7.0 for maximum stability
Synergistic Combinations: Works synergistically with copper (forming GHK-Cu), hyaluronic acid, and other peptides
Recommended Usage: Extremely low dosage (0.00002%–0.001%) is sufficient due to high potency
This peptide is widely used in serums, creams, lotions, masks, and eye care products across the global cosmetic market.
Packaging & Storage
| Packaging Option |
Specification |
| Sample / Trial |
1g per aluminum foil bag |
| Standard |
1kg per aluminum foil bag |
| Bulk |
Custom packaging available upon request |
Storage Conditions: Keep sealed, protected from light, and store in a cool, dry, well-ventilated area.
Shelf Life: 24 months from date of manufacture when stored properly.
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