Product Name: Glutathione (GSH)
Specification: ≥98%
CAS: 70-18-8
EINECS: 200-725-4
Molecular Weight: 307.323
Molecular Formula: C10H17N3O6S
Appearance: White to off-white crystalline powder
Product Description: Glutathione (GSH), a tripeptide containing a γ-amide bond and a sulfhydryl group, is composed of glutamic acid, cysteine, and glycine. It is present in nearly every cell of the body.
Product Overview
Glutathione (GSH) is a naturally occurring tripeptide composed of three amino acids — glutamic acid, cysteine, and glycine — linked by a γ-amide bond. It is present in nearly every cell of the human body and serves as the primary intracellular non-protein thiol antioxidant.
As a low molecular weight thiol-tripeptide, GSH plays a central role in antioxidant defense, detoxification, and cellular metabolism. It neutralizes reactive oxygen species (ROS), protects cellular components from oxidative damage, and maintains redox balance within cells. The thiol (-SH) group in GSH inhibits tyrosinase — the key enzyme in melanin synthesis — helping to reduce pigmentation and even out skin tone.
Our Glutathione is manufactured to ≥98% purity with strict quality control, suitable for applications across the cosmetics, food/nutraceutical, and pharmaceutical industries. The global glutathione market is experiencing robust growth, driven by increasing demand for antioxidant ingredients in skincare, dietary supplements, and pharmaceutical applications.
Solubility: Soluble in water, dilute alcohol, liquid ammonia, and methylformamide; insoluble in alcohol, ether, and acetone.
Functions: Glutathione helps maintain normal immune system function and possesses antioxidant, skin-whitening, spot-fading, anti-aging, immune-boosting, anti-tumor, and detoxifying properties. It is applicable not only in pharmaceuticals but also as a food additive and cosmetic ingredient.
Mechanism of Action
Glutathione exerts its biological activities through multiple pathways:
1. Antioxidant Defense
As the primary intracellular non-protein thiol, GSH neutralizes reactive oxygen species (ROS) such as hydroxyl radicals (·OH) and superoxide anions (·O₂⁻)
Protects lipids, proteins, and DNA from oxidative damage
Maintains the intracellular redox environment essential for cellular survival and metabolic activity
2. Skin Brightening & Tyrosinase Inhibition
The thiol (-SH) group inhibits tyrosinase, the key enzyme in melanin synthesis
Converts dark pigmentation (eumelanin) into light pigmentation (phaeomelanin)
Reduces melanin index and improves hyperpigmentation
3. Detoxification
Forms conjugates with harmful substances via glutathione S-transferase (GST), promoting cellular detoxification
Binds with heavy metals and xenobiotics, reducing toxicity
4. Immune Support
Key Benefits
| Application Area |
Key Benefits |
| Cosmetics & Skincare |
Skin whitening & brightening, anti-aging, wrinkle reduction, UV protection, antioxidant defense, hyperpigmentation improvement |
| Nutraceuticals / Dietary Supplements |
Immune system support, detoxification, liver health, cellular protection, anti-aging
|
| Pharmaceuticals |
Liver disease management, oxidative stress reduction, immune dysfunction support, oncology adjunctive therapy
|
| Food Industry |
Natural antioxidant, food preservation, functional food ingredient
|
Clinical studies have demonstrated that topical glutathione can significantly reduce ultraviolet-induced erythema (p=0.0003), decrease melanin index (p<0.05), and improve skin elasticity and wrinkle reduction (p<0.01).
Application Scenarios
| Application Area |
Recommended Dosage |
Product Forms |
| Serums & Essences |
0.1% – 2.0% |
Water-soluble formulations
|
| Creams & Lotions |
0.5% – 2.0% |
Emulsions, moisturizers |
| Face Masks |
0.5% – 1.5% |
Sheet masks, wash-off masks
|
| Sunscreens |
0.5% – 1.0% |
UV protection formulations
|
| Dietary Supplements |
50 – 500 mg/day |
Capsules, tablets, powders
|
| Pharmaceutical Formulations |
As per clinical protocol |
Injections, tablets |
GSH is incorporated into a wide variety of cosmetic formulations including serums, creams, lotions, masks, soothing gels, and water-soluble liquids or powders. Liposomal or microencapsulated forms are often used to improve stability and skin penetration.
Why Choose Our Glutathione?
✅ High Purity – ≥98.0% (HPLC), meeting cosmetic, food, and pharmaceutical grade standards
✅ Versatile Applications – Suitable for cosmetics, nutraceuticals, food additives, and pharmaceuticals
✅ Proven Efficacy – Clinically supported antioxidant, skin brightening, and anti-aging benefits
✅ Stable Supply – Reliable production capacity with consistent quality
✅ Quality Control – Strict monitoring of purity, heavy metals, and microbial limits
✅ Global Compliance – Meets international regulatory standards for cosmetic and food ingredients
Packaging & Storage
| Packaging Option |
Specification |
| Small Package |
1kg / aluminum foil bag |
| Bulk Package |
20-25kg / fiber drum |
| Custom Packaging |
Available upon request |
Storage Conditions: Store in a cool, dry place, protected from light, heat, oxygen and moisture. Keep container tightly closed.
Shelf Life: 24 months from date of manufacture when stored properly.
EN
