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acetyl dipeptide 1 cetyl ester993-0

Acetyl Dipeptide-1 Cetyl Ester

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Acetyl Dipeptide-1 Cetyl Ester
Acetyl Dipeptide-1 Cetyl Ester

Acetyl Dipeptide-1 Cetyl Ester

Acetyl Dipeptide-1 Cetyl Ester | Peptide for Sensitive Skin & Anti-Aging | TRPV1 Inhibitor Cosmetic Ingredient | ≥98% Purity

Acetyl Dipeptide-1 Cetyl Ester  - Soothing Peptide Powder | TRPV1 Inhibitor, Anti-Aging Cosmetic Raw Material

Acetyl Dipeptide-1 Cetyl Ester Supplier | Neuro-Soothing Peptide for Sensitive Skin Care Formulations

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Product Description
Product Name  Acetyl Dipeptide-1 Cetyl Ester
Appearance White to off-white particles or powder, slight characteristic odor
Purity ≥98.0%
Product Description A bioactive peptide that inhibits TRPV1 activation, reduces CGRP & SP release, and stimulates endorphin production. Ideal for sensitive skin & anti-aging cosmetics.

Acetyl Dipeptide-1 Cetyl Ester (also known as Calmosensine) is a synthetic dipeptide composed of acetylated tyrosine and arginine, esterified with cetyl alcohol. It is a bioactive peptide recognized for its dual skin-soothing and anti-aging properties, widely used as a cosmetic ingredient in sensitive skin care and anti-wrinkle formulations.

This lipophilic peptide features a cetyl ester moiety that enhances stratum corneum penetration, delivering active ingredients deep into the skin at low dosage with high potency. Backed by clinical studies and compliant with China and Japan cosmetic ingredient regulations, it offers a scientifically validated solution for the rapidly growing sensitive skin anti-aging market.
Product Characteristics Endogenous Soothing and Calming Peptide
Key Mechanisms of Action Acetyl Dipeptide-1 Cetyl Ester operates through a dual-pathway mechanism:

1. Neuro-Soothing (TRPV1 Inhibition)
Inhibits the activation of TRPV1 (transient receptor potential vanilloid 1), the skin's "sensitivity switch"
Reduces the release of pro-inflammatory mediators including CGRP (calcitonin gene-related peptide) and Substance P (SP)
Stimulates the release of β-endorphin, the body's natural "relaxation and pain-relief" messenger
Clinically shown to reduce erythema area by 43% and stinging sensation by 56%

2. Elasticity Activation (Anti-Aging)
Upregulates elastin mRNA expression, promoting the reconstruction of elastic fiber networks in the dermis
Protects collagen-producing fibroblasts from glycation damage
In vitro studies demonstrate 28% increase in elastin synthesis efficiency vs. control group; skin firmness improved by 19% after 4 weeks of use

3. Skin Barrier Enhancement
Increases gene expression of barrier function proteins: AQP3 (Aquaporin 3), FLG (Filaggrin), Caspase-14, and Cytokeratin 10
Reduces skin's neurological response to irritants and improves overall skin tolerance.
Key Benefits Soothes Sensitive Skin：Reduces neurogenic inflammation, improves redness, burning, and tingling sensations
Anti-Aging & Firming： Boosts skin elasticity, reduces dynamic wrinkles and sagging
Antioxidant Repair： Scavenges free radicals, reduces collagen degradation
Barrier Restoration： Strengthens skin barrier function and enhances moisture retention
Post-Procedure Recovery： Reduces post-treatment nerve sensitivity, accelerates barrier recovery
Solubility Practically insoluble in water
pH
(1 mg/mL, 1:1 ethanol-water)		 4.2–7.2
Storage Sealed in a cool, ventilated, dry place. Refrigeration recommended for extended shelf life.
Shelf Life 24 months
Application Scenarios Recommended usage level: 0.01% – 0.1%
Repair Creams / Serums： Rapid relief for seasonal sensitivity
Anti-Aging Firming Masks： Synergistic with other peptides for contour support
Premium Body Care： Improve neck and hand skin laxity
Post-Procedure Products： Reduce nerve sensitivity, accelerate barrier recovery
Moisturizing Creams / Facial Creams： Daily sensitive skin care
Eye Creams： Targeted anti-aging for delicate eye area
Packaging Options Self-sealing bags, aluminum foil bags, cartons, fiber drums (custom packaging available upon request)
Why Choose Us? ✅ High Purity – ≥98.0%, meeting cosmetic-grade standards
✅ Compliant – Listed in China and Japan cosmetic ingredient directories
✅ Versatile – Suitable for a wide range of skincare formulations
✅ GMP Production – Manufactured under strict quality control standards

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