Product Title
Bitter Melon Peptides (Low-Molecular-Weight) | 98% Purity Food Grade | Plant-Based Bioactive Peptide for Metabolic Wellness
Product Name: Bitter Melon Peptides / Bitter Melon Peptide / Bitter Melon Low-Molecular-Weight Peptides
Extraction Source: Bitter Melon (Momordica charantia L.) fruit
Grade: Food Grade
Purity (Peptide Content): ≥98%
Molecular Weight: <500 Daltons (predominantly oligopeptides)
Particle Size: 100% passes 80–100 mesh
Solubility: Instant dissolving, clear and transparent in water
Shelf Life: 24 months (stored in cool, dry, light-protected conditions)
Product Overview
Bitter melon (Momordica charantia L.) has been traditionally used for centuries in Asian, African, and South American herbal systems for supporting healthy glucose metabolism and overall metabolic balance. Through advanced enzymatic hydrolysis and membrane separation technologies, we have isolated low-molecular-weight peptides (average molecular weight <500 Da) from the fruit, yielding a highly bioavailable oligopeptide concentrate.
These small peptides are rapidly absorbed in the gastrointestinal tract and exert potent biological activities, including insulin-like hypoglycemic effects, antioxidant defense, immunomodulation, and pancreatic β‑cell protection. Unlike intact proteins, these oligopeptides bypass the need for extensive digestion, delivering active amino acid sequences directly to target tissues.
Our Bitter Melon Peptides are manufactured to ≥98% purity (peptide content) using food-grade processing, with instant solubility that produces a crystal-clear solution — an ideal property for liquid formulations, powdered beverages, and clear nutritional drinks. The product complies with international food safety standards and is widely exported to functional food, nutraceutical, and sports nutrition markets worldwide.
Key Specifications
| Parameter |
Specification |
| Product Name |
Bitter Melon Peptides (Low-MW) |
| Source |
Bitter Melon (Momordica charantia L.) fruit |
| Grade |
Food Grade |
| Peptide Content |
≥98% |
| Molecular Weight |
<500 Daltons (avg. ~300–500 Da) |
| Appearance |
Light yellow to off-white powder |
| Solubility |
Instant dissolving, clear solution in water |
| Particle Size |
100% through 80–100 mesh |
| Major Components |
Natural bitter melon oligopeptides, amino acids, charantin, momordicosides, alkaloids (quinine), vitamin C, trypsin inhibitors |
| Heavy Metals |
Compliant with food-grade limits |
| Storage |
Sealed, protected from light, stored in cool (≤25°C), dry, ventilated area |
| Shelf Life |
24 months |
Mechanisms of Action & Bioactivities
Bitter Melon Peptides exert their health benefits through multiple validated pathways:
1. Hypoglycemic & Insulin-Mimetic Action
Active peptide components (e.g., polypeptide-p, plant insulin) exhibit insulin-like activity by binding to insulin receptors and activating downstream signaling pathways
Enhance glucose uptake in peripheral tissues (muscle and adipose)
Suppress α-glucosidase activity, delaying intestinal carbohydrate absorption and reducing postprandial blood glucose spikes
Promote hepatic glycogen synthesis and inhibit gluconeogenesis
Protect and regenerate pancreatic β‑cells, improving endogenous insulin secretion
2. Antioxidant & Free-Radical Scavenging
Rich in hydrophobic amino acid residues (e.g., leucine, isoleucine) with strong radical-scavenging capacity
Neutralize reactive oxygen species (ROS) generated during hyperglycemic stress
Alleviate oxidative damage to vascular endothelium and pancreatic tissue
3. Immunomodulatory & Anti-Inflammatory
Modulate cytokine profiles (reduce TNF‑α, IL‑6, increase IL‑10)
Stimulate macrophage activity and enhance natural killer (NK) cell function
Support gut-associated lymphoid tissue (GALT) for systemic immune balance
4. Lipid & Weight Management
Peptide fractions have shown lipolytic activity, promoting fatty acid oxidation
Inhibit pancreatic lipase, reducing dietary fat absorption
Support healthy serum triglyceride and cholesterol levels
5. Cardiovascular & Metabolic Support
Peptide sequences with ACE-inhibitory activity help maintain healthy blood pressure
Improve endothelial function and reduce oxidative stress markers
Synergistic effects with charantin, alkaloids, and saponins naturally present in the extract
Key Benefits
| Application Field |
Key Benefits |
| Dietary Supplements (Capsules, Tablets) |
Supports healthy blood sugar balance, enhances glucose tolerance, aids in insulin sensitivity |
| Functional Foods |
Low‑glycemic index ingredient for diabetic-friendly snacks, meal replacements, and cereals |
| Beverages & Powders |
Instant soluble with high clarity – perfect for ready‑to‑drink shakes, protein waters, and nutritional drinks |
| Sports Nutrition |
Accelerates post‑exercise glycogen repletion; supports metabolic recovery and oxidative stress reduction |
| Healthy Aging & Wellbeing |
Provides pancreatic support and systemic antioxidant protection for long‑term metabolic wellness |
Application Scenarios / 应用场景
| Application Form |
Recommended Dosage |
Product Examples |
| Powdered drink mixes |
100 – 500 mg per serving |
Single‑serve sachets, bulk tubs |
| Capsules / Tablets |
150 – 300 mg per cap (2–3 caps/day) |
Hard gelatin capsules, vegetarian capsules |
| Ready‑to‑drink (RTD) beverages |
0.1% – 0.5% (w/v) |
Clear functional waters, protein shakes |
| Meal replacement bars / shakes |
1% – 5% (w/w) |
Protein bars, meal‑replacement powders |
| Functional confectionery |
0.5% – 2.0% |
Gummies, chews, lozenges |
| Nutritional supplements (liquid) |
As per formulation |
Liquid vials, ampoules, syrups |
Note: Dosage may vary depending on specific product claims and regional regulations. We recommend conducting stability and efficacy testing for your final formulation.
Why Choose Our Bitter Melon Peptides?
✅ High Purity & Potency – ≥98% peptide content ensures consistent bioactivity and low excipient load
✅ True Low‑MW – <500 Da guarantees rapid absorption and excellent oral bioavailability
✅ Instant Solubility – Dissolves readily in water with crystal clarity – no sedimentation, ideal for clear beverages
✅ Comprehensive Active Profile – Naturally retains charantin, momordicosides, alkaloids, vitamin C, and trypsin inhibitors for synergistic effects
✅ Food Grade Assurance – Manufactured under HACCP/ISO‑certified facilities; full traceability from raw fruit to final powder
✅ Customizable Packaging – Available in 1kg foil bags (sample) and 10kg cartons with inner liner (bulk), or tailored to your needs
✅ Global Regulatory Compliance – Meets EU, US, and Asian food supplement standards; full COA provided with each batch
Packaging & Storage
| Packaging Option |
Specification |
| Sample / Small batch |
1 kg / aluminum foil bag (heat‑sealed) |
| Bulk / Standard |
10 kg net weight per carton, lined with transparent polyethylene bag |
| Custom |
Available upon request (various drum, pail, or bag sizes) |
Storage Conditions: Keep sealed, protected from direct sunlight, and store in a cool (≤25°C), dry, and well‑ventilated area. Avoid high temperature and humidity.
Shelf Life: 24 months from date of manufacture under recommended storage.
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